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Washington Nationals vs Cincinnati Reds Prediction 5/2/25 MLB Picks

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Cincinnati Reds (17-15) vs Washington Nationals (14-18)

May 2, 2025 at 06:10 PM EDT

The Line: Betting Odds: Cincinnati Reds -166 / Washington Nationals +140 — Over/Under: 8

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The Washington Nationals and Cincinnati Reds meet Friday in MLB action at Great American Ball Park. Here’s a Washington Nationals vs Cincinnati Reds Prediction. This article will include a Washington Nationals vs Cincinnati Reds Pick.

Washington Nationals Betting Preview

The Washington Nationals are 14-18 on the year and play the Guardians, Cardinals, and Braves next. The Washington Nationals are batting .238 on the season, have a .305 OBP, and a .384 slugging percentage. The Washington Nationals’ pitching staff has a 5.17 ERA and a 1.42 WHIP. Keibert Ruiz leads the Washington Nationals with 32 hits and 13 RBI, while James Wood and Nathaniel Lowe have combined for 59 hits and 46 RBI. 

Mitchell Parker gets the ball for the Washington Nationals, and he is 3-1 with a 2.65 ERA and 20 strikeouts this season. This will be Parker’s first career game against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 17-15 on the year and play the Braves, Astros, and White Sox next. The Cincinnati Reds are batting .249 on the season, have a .327 OBP, and a .395 slugging percentage. The Cincinnati Reds pitching staff has a 3.53 ERA and a 1.09 WHIP. TJ Friedl leads the Cincinnati Reds with 34 hits and 12 RBI, while Elly De La Cruz and Gavin Lux have combined for 66 hits and 39 RBI.

Hunter Greene gets the ball for the Cincinnati Reds, and he is 3-2 with a 2.70 ERA and 43 strikeouts this season. This will be Greene’s second career game against the Washington Nationals.

Why the Cincinnati Reds will win

  • The home team has won each of the last four games between the Nationals and Reds.
  • The Nationals have lost six of their last seven games against NL Central opponents that held a winning record.
  • The Reds have covered the run line in each of their last five games against National League opponents after playing the previous day.
  • The Nationals have failed to cover the run line in four of their last five night games against National League opponents following a road win.
  • The Nationals have trailed after 3 innings in five of their last six games.
  • The Reds have led after 5 innings in four of their last five night games at Great American Ball Park against National League opponents.

Why the Washington Nationals will win

  • The underdogs have won each of the Reds’ last three games.
  • The Reds have lost three of their last four games as favorites against NL East opponents following a win.
  • The Nationals have covered the run line in nine of their last 10 games at Great American Ball Park against teams that held a winning record.
  • The Reds have failed to cover the run line in six of their last seven home games against the Nationals following a win.

Cincinnati Reds Player Prop Facts

  • TJ Friedl has hit a home run in each of his last two appearances against the Nationals at Great American Ball Park.
  • Hunter Greene has recorded a win in four of his last five appearances with the Reds as home favorites against NL opponents.
  • Hunter Greene has recorded eight or more strikeouts in six of his last seven appearances at Great American Ball Park.
  • Elly De La Cruz has recorded at least one hit in each of the Reds’ last 13 games against the Nationals.
  • Tyler Stephenson has recorded at least one Single in nine of his last 10 appearances in night games against teams that held a losing record.
  • Tyler Stephenson has recorded at least one RBI in each of his last four appearances in night games against NL teams that held a losing record.
  • Will Benson has recorded a Double in each of the Reds’ last three games against the Nationals at Great American Ball Park.
  • Tyler Stephenson has scored at least one run in each of his last seven appearances in night games against teams that held a losing record.
  • Gavin Lux ranks 6th amongst qualified players for On Base Percentage (.410) this season.

Washington Nationals Player Prop Facts

  • Josh Bell has hit at least one home run in five of his last 10 road appearances against NL Central opponents that held a winning record.
  • Luis Garcia has recorded a Double in each of his last three appearances at Great American Ball Park against NL Central opponents that held a winning record.
  • Nathaniel Lowe has recorded at least one RBI in each of the Nationals’ last four games against NL opponents.
  • Luis Garcia has scored at least one run in 13 of his last 14 Friday night appearances against teams that held a winning record.
  • CJ Abrams has recorded at least one Single in eight of his last nine appearances in night games against NL teams that held a winning record.
  • Amed Rosario has recorded at least one hit in each of his last 11 appearances against the Reds at Great American Ball Park.

Washington Nationals vs Cincinnati Reds Prediction

You can make a case for the Nats and Parker, as he’s been strong this season, which includes allowing 19 hits and 11 earned runs in his last 31 innings. I’m not mad at it. I’m still leaning toward the Reds and the reasonable price. The Reds are playing their best ball of the season, and Greene is looking like one of the best young arms in the sport. In the last 31.2 innings, Greene has allowed 22 hits and nine runs while striking out 35. In 19 home innings, Greene has a 1.42 ERA and .123 allowed batting average. I can’t step in front of that. I’ll roll with the Reds on Friday night.

Randy Chambers's Pick: Cincinnati Reds -166