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New York Yankees vs Seattle Mariners Prediction 5/13/25 MLB Picks

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Seattle Mariners (22-18) vs New York Yankees (24-17)

May 13, 2025 at 09:40 PM EDT

The Line: Betting Odds: Seattle Mariners +114 / New York Yankees -135 — Over/Under: 7

(Get latest betting odds)

The New York Yankees are visiting the Seattle Mariners on Tuesday, May 13th at the T-Mobile Park in the second game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs Seattle Mariners Prediction. We will examine:

The Seattle Mariners’ recent form and player performance

The New York Yankees’ recent form and player performance

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends and streaks involving the New York Yankees

Recent betting trends in games played between the New York Yankees vs Seattle Mariners

A summary that ties it all together and produces a favorable betting outcome for the New York Yankees vs Seattle Mariners game

Seattle Mariners Preview

The Seattle Mariners have a 22-18 record this season and are sitting in first place in the AL West. The Mariners have a 12-10 home record and 25-13 in over/under. They are coming off a 5-11 home defeat by the Yankees and have now lost four consecutive games. Over is 9-2 in their last 11 games, and they are playing the Padres and the White Sox next.

The Mariners have a .242 batting average this season, a .331 OBP, and a .408 Slugging percentage. Seattle’s pitching staff has a 4.17 ERA and 1.36 WHIP. JP Crawford leads the Mariners with 37 hits and is the team’s best hitter with a .274 batting average. Jorge Polanco leads the team in RBI with 29, while Cal Raleigh adds a team-high 13 home runs.

Bryan Woo (R) will take the mound for the Mariners, and he has a 4-1 record, 3.25 ERA, and 0.92 WHIP. He has been far better at home, where he has only two earned runs in 13 innings of work across two starts, for a 1.38 ERA. He is coming off his worst start of the season, where he gave up 5 runs in 6 innings of work, but the Mariners still managed to win against the Athletics 6-5. In his previous home start against the Yankees last season, Woo got torched as he gave up 7 runs in 4.2 innings of work, and the Yankees destroyed the Mariners 11-2.  

New York Yankees Preview

The New York Yankees have a 24-17 record this season and are sitting in first place in the AL East. The Yankees have an 11-9 road record and are 20-19 in over/under. They are coming off an 11-5 road victory against the Mariners, and are 5-1 in their last 6 games. Over is 5-1 in their last 6 games, and they are playing the Mets and the Rangers next.

The Yankees have a .267 batting average this season, a .351 OBP, and a .489 Slugging percentage. New York’s pitching staff has a 3.74 ERA and 1.20 WHIP. Aaron Judge leads the Yankees with 65 hits, 40 RBI, and 14 home runs, while also being the team’s best hitter, with a .414 batting average.

Max Fried (L) will take the mound for the Yankees, and he has a 4-0 record, 1.05 ERA, and 0.91 WHIP. He has been even better on the road, with just one earned run in 20.1 innings of work across three starts, for a 0.44 ERA. He has given up just one run in 27.2 innings of work across his last four starts. In his only start against the Mariners last season, he had a shutout performance in 6 innings of work.  

Why the Seattle Mariners will win

  • The Mariners have won five of their last six games as underdogs against American League opponents following a loss.
  • The Yankees have lost three of their last four games as favorites against American League opponents following a road win.
  • The Mariners have covered the run line in eight of their last nine games as underdogs against American League opponents following a loss.
  • The Yankees have failed to cover the run line in six of their last seven games as favorites following a road win.
  • The Mariners have won the first inning in four of their last five games against AL East opponents that held a winning record.
  • The Mariners have led after 3 innings in seven of their last eight home night games.
  • The Mariners have led after 5 innings in three of their last four home games against American League opponents that held a winning record.

Why the New York Yankees will win

  • The road team has won each of the Mariners’ last six games.
  • The Mariners have lost eight of their last nine night games against AL East opponents.
  • The Mariners have failed to cover the run line in eight of their last nine games.
  • The Yankees have covered the run line in seven of their last eight games against AL West opponents.
  • The Yankees have led after 3 innings in four of their last five night games against AL West opponents that held a winning record.
  • The Yankees have led after 5 innings in each of their last five night games against AL West opponents that held a winning record.

Total Runs Facts

  • Each of the Mariners’ last nine home games have gone OVER the total runs line.
  • Each of the Yankees’ last six games against AL West opponents have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Mariners’ last nine games as underdogs.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Yankees’ last eight games.

Matchup/League Facts

  • The Mariners rank 2nd in the league for walks this season (164).
  • The Mariners are one of only three teams in the league to rank top 10 in both steals and home runs this season.
  • The Yankees rank 1st in the league for runs scored this season (246).
  • The Yankees rank 1st in the league for home runs this season (74).

New York Yankees vs Seattle Mariners Prediction

The Yankees are 5-1 in their last 6 meetings against the Mariners, and the over is 6-3 in their last 9 meetings. In this New York Yankees vs Seattle Mariners Prediction, the Yankees are coming as -135 road favorites. The Yankees are rightfully favored, as they have been red-hot lately, with just one loss in their last six games, while the Mariners are on a slide with four consecutive losses.

Yankees’ offense has been clicking lately, as they have scored 10+ runs in three of their last four games, and are facing Bryan Woo, who is off his worst start of the season, and got shelled in his only home start against the Yankees last season. On the other hand, Max Fried looks unhittable for the Yankees, and the Mariners are weaker against lefties. Take the Yankees on the moneyline in the first 5 innings of the game.

Nikos Lagouretos's Pick: New York Yankees F5 ML