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Minnesota Twins vs Boston Red Sox Prediction 5/2/25 MLB Picks
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Boston Red Sox (17-16) vs Minnesota Twins (13-19)
May 2, 2025 at 07:10 PM EDT
The Line: Betting Odds: Boston Red Sox -108 / Minnesota Twins -112 — Over/Under: 9

The Minnesota Twins and Boston Red Sox meet Friday in MLB action at Fenway Park. Here’s a Minnesota Twins vs Boston Red Sox Prediction. This article will include a Minnesota Twins vs Boston Red Sox Pick.
Minnesota Twins Betting Preview
The Minnesota Twins are 13-19 on the year and play the Orioles, Giants, and Brewers next. The Minnesota Twins are batting .235 on the season, have a .308 OBP, and a .369 slugging percentage. The Minnesota Twins pitching staff has a 3.52 ERA and a 1.20 WHIP. Ty France leads the Minnesota Twins with 32 hits and 18 RBI, while Byron Buxton and Carlos Correa have combined for 53 hits and 26 RBI.
Joe Ryan gets the ball for the Minnesota Twins, and he is 2-2 with a 3.18 ERA and 39 strikeouts this season. Ryan is 3-2 with a 3.38 ERA and 32 strikeouts in his career against the Boston Red Sox.
Boston Red Sox Betting Preview
The Boston Red Sox are 17-16 on the year and play the Rangers, Royals, and Tigers next. The Boston Red Sox are batting .250 on the season, have a .330 OBP, and a .418 slugging percentage. The Boston Red Sox pitching staff has a 4.05 ERA and a 1.30 WHIP. Alex Bregman leads the Boston Red Sox with 42 hits and 26 RBI, while Jarren Duran and Trevor Story have combined for 72 hits and 33 RBI.
Brayan Bello gets the ball for the Boston Red Sox, and he is 2-0 with a 3.27 ERA and 7 strikeouts this season. This will be Bello’s second career game against the Minnesota Twins.
Why the Boston Red Sox will win
- The Twins have lost each of their last five games as favorites against AL East opponents.
- The Red Sox have won seven of their last eight games against the Twins at Fenway Park following a loss.
- The Twins have failed to cover the run line each of their last seven road games against AL East opponents that held a winning record.
- The Red Sox have covered the run line in six of their last seven home games against the Twins following a loss.
- The Twins have trailed after 5 innings in each of their last seven night games against AL East opponents that held a winning record.
- The Red Sox have led after 3 innings in five of their last six home games against AL Central opponents that held a losing record.
Why the Minnesota Twins will win
- The Twins have won each of their last six Friday night road games against AL East opponents.
- The Red Sox have lost each of their last four night games at Fenway Park following a loss.
- The Twins have covered the run line in each of their last six Friday road games against AL East opponents.
- The Red Sox have failed to cover the run line in eight of their last 10 home games after playing the previous day.
Boston Red Sox Player Prop Facts
- Wilyer Abreu has hit a home run in two of his last three appearances against AL Central opponents.
- Jarren Duran has recorded a Double in three of the Red Sox’s last four home games against AL opponents.
- Rafael Devers has recorded at least one Single in each of his last seven appearances with the Red Sox as home underdogs against AL opponents.
- Alex Bregman has scored at least one run in each of his last five home appearances against AL opponents that held a losing record.
- Alex Bregman has recorded at least one hit in each of the Red Sox’s last 11 games.
- Connor Wong has recorded an RBI in each of his last four home appearances against AL Central opponents.
- Jarren Duran ranks T4th in the league in Hits (39) this season.
Minnesota Twins Player Prop Facts
- Ty France has hit a home run in three of the Twins’ last six road games against AL opponents.
- Ty France has recorded at least one Double in four of his last five appearances at Fenway Park against AL East opponents that held a winning record.
- Joe Ryan has recorded a win in three of his last four appearances against AL opponents.
- Joe Ryan has recorded eight or more strikeouts in three of his last four appearances against AL opponents that held a winning record.
- Carlos Correa has scored at least one run in eight of his last nine appearances at Fenway Park against AL East opponents that held a winning record.
- Ty France has recorded at least one hit in each of his 11 previous road appearances against the Red Sox.
- Jonah Bride has recorded at least one RBI in each of his last four road appearances against AL East opponents.
- Christian Vazquez has recorded at least one Single in seven of his last eight appearances against AL opponents at Fenway Park.
Minnesota Twins vs Boston Red Sox Prediction
Ryan has been solid enough to give the Twins a look, as he’s allowed just 12 runs in 34 innings while striking out 39. The problem is the Twins don’t string together enough offense to trust, and it’s led to a lot of disappointing results. Bello has just 11 innings under his belt this season, but we know what he’s capable of when he’s right, and he hasn’t been terrible given the small sample size. Bello has allowed 10 hits and four runs in those frames. A pick ’em price, I have to give the edge to the Red Sox at home. Give me some plus money and I’d give the Twins a look. That’s not the case here. I’ll side with the Red Sox.