Boston Red Sox vs Detroit Tigers Prediction 5/13/25 MLB Picks

The Boston Red Sox and the Detroit Tigers meet Tuesday in MLB action from Comerica Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Detroit Tigers prediction.

Starting Pitching Matchup

The Boston Red Sox will send out Brayan Bello for the start here, and Bello is 2-0 with a 2.01 ERA and 13 strikeouts. In his career, Bello is 0-1 with a 6.55 ERA and 10 strikeouts against Detroit. The Detroit Tigers will send out Tyler Holton for the start here, and Holton is 2-2 with a 3.12 ERA and 17 strikeouts this season. This will be Holton’s first career start against Boston.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from their series-opening 14-2 loss at the hands of the Tigers on Monday to slip to 22-21 on the year. After this series, the Red Sox will head home for a series against the Atlanta Braves.

Red Sox Looking To Bounce Back

Alex Bregman leads the Red Sox with 51 hits, including a team-high 15 doubles, along with 9 home runs and 31 RBIs, while Rafael Devers has added 45 hits with 12 doubles, 7 home runs and 31 RBIs this season. Trevor Story added 39 hits with 6 home runs, 19 RBIs, and 8 stolen bases, while Jarren Duran has 46 hits with 9 doubles, 4 triples, 2 home runs, 21 RBIs, and a team-high 11 stolen bases. Kristian Campbell added 34 hits with 8 doubles, 4 homers, and 13 RBIs, while Wilyer Abreu has 11 home runs with 27 RBIs and 4 stolen bases, and Ceddanne Rafaela has 2 homers, 2 triples, 15 RBIs, and 7 stolen bases this season.

Why the Boston Red Sox will win

• The Tigers have lost seven of their last eight night games against the Red Sox following a home win.
• The Red Sox have won each of their last four games against AL Central opponents following a road loss.
• The Tigers have failed to cover the run line in each of their last six games as underdogs against the Red Sox following a win.
• The road team has covered the run line in seven of the Tigers’ last eight games.

Boston Red Sox Player Prop Facts

• Wilyer Abreu has hit at least one home run in three of the Red Sox’s last four games as favorites.
• Alex Bregman has recorded at least one Double in three of his last four appearances with his team as a road favorite against the Tigers.
• Abraham Toro has recorded at least one RBI in seven of his last eight appearances against the Tigers.
• Abraham Toro has scored at least one run in five of his last six appearances at Comerica Park.
• Rafael Devers has recorded at least one Single in each of the Red Sox’s last six games against AL Central opponents that held a winning record.
• Rafael Devers has recorded at least one hit in each of the Red Sox’s last 12 road games.
• Alex Bregman ranks T6th in the league in Hits (51) this season.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to add on to their blowout win over the Red Sox on Monday to improve to 27-15 on the year. After this series, the Tigers will head on the road for a series against the Toronto Blue Jays.

Tigers Looking To Continue Strong Play At Home

Spencer Torkelson has 36 hits along with a .238 batting average, including a team-high 10 home runs, 11 doubles, and 33 RBIs. Kerry Carpenter also has 9 home runs and 21 RBIs, while Riley Greene has 41 hits with 6 doubles, 9 home runs and 24 RBIs, but also has a team-high 48 strikeouts this season. Dillon Dingler has 4 home runs and 16 RBIs, and Zack McKinstry’s added 6 doubles, 3 triples, a home run, and 16 RBIs of his own, along with 36 hits this season. Javier Baez has added 36 hits and 8 doubles as well this season.

Why the Detroit Tigers will win

• The Tigers have won five of their last six games as underdogs against AL East opponents.
• The Red Sox have lost each of their last three games as road favorites.
• The Tigers have covered the run line each of their last seven home games against American League opponents that held a winning record.
• The Red Sox have failed to cover the run line in each of their last three games as favorites against AL Central opponents.

Detroit Tigers Player Prop Facts

• Gleyber Torres has hit a home run in each of his last two home appearances against the Red Sox.
• Gleyber Torres has recorded at least one RBI in each of his last seven appearances against the Red Sox.
• Gleyber Torres has scored at least one run in each of his last seven home appearances against AL opponents that held a winning record.
• Gleyber Torres has recorded at least one Single in each of his last nine appearances with his team as a home underdog against AL opponents.
• Parker Meadows has recorded at least one hit in each of his last 13 appearances in night games.
• Spencer Torkelson ranks T10th in the league in Home Runs (10) this season.

Total Runs Facts

• Each of the Tigers’ last five games as underdogs have gone OVER the total runs line.
• Each of the Red Sox’s last five games as favorites against the Tigers have gone OVER the total runs line.

Boston Red Sox vs. Detroit Tigers Prediction

I’m on the Red Sox here. I think it’s worth taking a shot on here with Boston, considering that the Tigers put a whooping on Boston on Monday and now have one of their best options going in Brayan Bello who has looked solid out of the gate and the Red Sox have won all four of his starts so far this season. On the other side, I’m not sure if it’s a bullpen game for the Tigers or if Holton is just an opener, but I don’t love this spot for Detroit, and I think this is Boston’s best shot at a win in this series. Give me the Red Sox here.

Chris Ruffolo's Pick: Boston Red Sox -118